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    嚴重的創傷性腦損傷需要監測顱壓嗎?
    原作者: Haney Mallemat,肖鋒譯 文章來源: 中華急診醫學雜志編輯部 發布日期:2013-03-04

    Title: Do Monitors Matter?

    題目:需要監測(腦壓)嗎?

    Author 作者: Haney Mallemat

    Management of patients with severe traumatic brain injury (TBI) typically involves the use of invasive intra-parenchymal pressure monitors. Although use of these monitors is recommended by TBI management guidelines, good quality evidence of benefit is lacking.

    嚴重的創傷性腦損傷(TBI)通常要使用侵入性腦內壓力監測。雖然這些監測是在TBI處理指南中建議的,但并沒有足夠有力的支持證據。

    A recently published study evaluated the outcomes of TBI patients using a management protocol incorporating either an intracranial pressure (ICP) monitor compared to use of the clinical exam PLUS serial neuroimaging; a total of 324 patients were prospectively randomized into either group.

    一個最新發表的文章對TBI病人在用顱內壓監測和用臨床檢查包括系列腦影像方案的預后進行了評價;一共有324病人被前瞻性地隨機分到了任何一組。

    The primary study outcome was a composite of survival, impaired consciousness, and functional status at both three and six months.

    主要的研究指標包括在3和6個月時的生存率,神志障礙,和功能狀態。

    The results of the study did not show a significant difference in the:

    研究結果顯示,在如下幾個方面沒有明顯差別:

    • Primary outcome 主要預后指標

    • Median length of ICU stay 平均ICU住院時間

    • Distribution of serious adverse events 嚴重的惡性事件的發生

    Bottom line: This study suggests that clinical exam PLUS serial neuroimaging may perform as well as invasive intra-parenchymal monitors for guiding therapy in TBI patients.

    要點:這個研究顯示,在指導TBI病人的治療上,臨床檢查加上系列神經影像與侵入性腦內壓監測有同樣的作用。

    References 參考文獻

    Chestnut, R. et al. A Trial of Intracranial-Pressure Monitoring in Traumatic Brain Injury. NEJM 2012 Dec 12.

    文章來源:中華急診醫學雜志編輯部

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