Title: 10 New Drugs and Devices from 2011 - 2012 That Might Change Your EM Practice
題目:在2011和2012年出現的將改變你的急診臨床的10個新藥或新儀器
Author: Feng Xiao (肖鋒)
1. Xarelto® (rivaroxaban) - a Factor Xa inhibitor for treating venous thromboembolic disease (VTE)
拜瑞妥®(利伐沙班) - Xa因子抑制劑治療靜脈血栓栓塞癥(VTE)
For prophylaxis of deep vein thrombosis (DVT) in adults undergoing hip and knee replacement surgery; for stroke prophylaxis in patients with non-valvular atrial fibrillation; on November 2, 2012, for the treatment of patients with DVT and PE and for long-term treatment to prevent recurrence.
預防成人髖關節和膝關節置換手術后深靜脈血栓(DVT)形成;預防非瓣膜性房顫患者腦卒中的產生;2012年11月2日,DVT和肺動脈栓塞的治療和預防復發。
2. Eliquis® (apixaban) - another direct factor Xa inhibitor
Eliquis®(阿哌沙班) - 另一個直接Xa因子抑制劑
for reducing the risk of stroke and systemic embolism in patients with atrial fibrillation that is not caused by a heart valve problem.
可減少非心臟瓣膜問題引起的房顫導致腦卒中和全身性栓塞的風險
3. Brilinta® (ticagrelor) - an antiplatelet agent
Brilinta®(替卡格雷) - 一種抗血小板劑
for secondary prevention of stent thrombosis, cardiovascular death, and heart attack in patients with acute coronary syndrome (ACS).
急性冠脈綜合征(ACS)患者的支架內血栓形成,心血管死亡和心肌梗塞的二級預防。
4. Tudorza® (aclidinium bromide) - an inhalational anticholinergic agent for COPD / emphysema
Tudorza®(阿地溴銨) - 治療COPD /肺氣腫的吸入性抗膽堿能劑
Twice-daily dosing. Ipratropium bromide (Atrovent®), four-time-daily dosing and tiotropium (Spiriva®) once-daily
每日兩次。異丙托溴銨??(愛喘樂®),每日四次;噻托溴銨(思力華®)每日一次
5. Sklice® (ivermectin) - topical treatment of head lice infestation
Sklice®(伊維菌素) - 外用治療頭虱
One time treatment 一次性治療
6. Subsys® (fentanyl sublingual spray formulation for breakthrough cancer pain)
SUBSYS®(芬太尼舌下噴霧制劑控制癌癥疼痛)
Healthcare professionals who prescribe Subsys® on an outpatient basis must first enroll in the Transmucosal Immediate Release Fentanyl Risk Evaluation and Mitigation Strategy
門診醫生開SUBSYS®的處方權,必須向聯邦粘膜芬太尼風險評估和控制戰略部門申請
7. Dificid® (fidaxomicin) - antibiotic specific for treatment of Clostridium difficile
Dificid®(非達霉素) - 治療難辨梭狀芽孢桿菌的特異性抗生素
similar efficacy to vancomycin
與萬古霉素有相似的療效
8. Rectiv® (nitroglycerin ointment 0.4%) - topical therapy for anal fissure Rectiv®(硝酸甘油軟膏0.4%) - 外用治療肛裂
The recommended dosage is one inch of ointment (375 mg of ointment equivalent to 1.5 mg of nitroglycerin) applied intra-anally every 12 hours up to three weeks
推薦用量為一英寸(375毫克,相當于1.5毫克硝酸甘油軟膏)肛門內,每12小時一次,可用三個星期
9. Auvi-Q® - a talking dispenser of epinephrine / adrenaline
Auvi-Q® - 一個會說話的腎上腺素注射器
Auvi-Q® is an epinephrine auto-injector that is easy to carry and “talks” to you how to use it
Auvi-Q®是一種腎上腺素自動注射器,很容易攜帶并“語音指示”你如何使用它
10. Zio-Patch® - a device for monitoring dysrhythmias in outpatients
齊奧粘片® - 一種在院外監測心律失常的設備
The Zio® Patch is a single-use, noninvasive waterproof continuous monitoring patch worn on the chest that provides continuous monitoring for up to 14 days.
齊奧粘片®是一次性使用的,非侵入性并防水的連續心電監測粘片。它戴在胸前,提供長達14天的連續心電監測。
Reference 參考文獻:
Joe Lex. New Drugs and Devices from 2011-2012 That Might Change Your Practice http://www.emedhome.com/features_archive_detail.cfm
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